Green tea ‘may keep HIV at bay’
BBC - Drinking green tea could help in the fight against HIV, research suggests.
Scientists found a component called epigallocatechin gallate (EGCG) prevents HIV from binding to immune system cells by getting there first.
Once EGCG has bound to immune system cells there is no room for HIV to take hold in its usual fashion. Read more
New drugs awaiting discovery in Chinese herbs?
The first large-scale computer screenings of Chinese herbs — commonly used in traditional Chinese medicine — has revealed a wide variety of compounds with potential for use in treating HIV/AIDS, cancer, Alzheimer’s Disease, arthritis and other diseases, according to scientists in London.
In an article scheduled for the March 26 issue of the ACS’ Journal of Chemical Information and Modeling, a bi-monthly publication, David J. Barlow and colleagues note that such in silico research is becoming increasingly effective in identifying promising compounds that could be candidates for drug development. In silico (”in silicon”) means research done on computers or via computer simulation and has joined the in vivo and in vitro experiments traditionally used in the life sciences.
The researchers screened a database of chemical structures of Chinese herbal constituents from 240 species of plants for possible activity against various diseases. About 62% of the species were found to contain chemicals with characteristics required for activity against at least one disease and 53% against two or more diseases.
The study also describes corroborative evidence from the scientific literature that supported many of the computer predictions. In a companion article in the journal, the researchers describe the herbal databases.
ARTICLE #2
“Virtual Screening of Chinese Herbs with Random Forest”
“Phytochemical Databases of Chinese Herbal Constituents and Bioactive Plant Compounds with Known Target Specificities”
CONTACT:
David J. Barlow, Ph.D.
King’s College London
London, United Kingdom
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The American Chemical Society — the world’s largest scientific society — is a nonprofit organization chartered by the U.S. Congress and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.
Contact: Michael Woods
American Chemical Society
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